Rational Polypharmacy:
Treating Bipolar Disorder During Acute and Maintenance Phases


An Internet CME-Certified Monograph

March 2009

Sponsorship and Support
Sponsored by Veritas Institute for Medical Education, Inc. Supported by an educational grant from Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. administered by Ortho-McNeil Janssen Scientific Affairs, LLC.

Method of Participation
If you choose to print out this monograph and read it offline, you may complete the CME Activity Evaluation and Request for Credit Form at the end, and fax or mail the form to Veritas Institute for Medical Education, Inc. at the number or address listed. You will receive a statement of credit within 2 weeks.

If you choose to read the monograph and complete the CME Activity Evaluation and Request for Credit Form online, you can receive your statement of credit immediately and print it for your records.

This activity is provided free of charge to participants.

Intended Audience
Psychiatrists

Effective Dates
March 2009 to March 31, 2010

Estimated Time to Complete
2.5 hours (150 minutes)

Accreditation Statement
Veritas Institute for Medical Education, Inc. is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit
Veritas Institute for Medical Education, Inc. designates this educational activity for a maximum of 2.5 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Financial Disclosure Summary
In accordance with the ACCME’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Disclosures are as follows:

Roger S. McIntyre, MD, FRCPC: AstraZeneca Pharmaceuticals LP (consultant, speakers bureau), Biovail Pharmaceuticals (consultant, speakers bureau), Bristol-Myers Squibb Company (consultant, speakers bureau), France Foundation (consultant, speakers bureau), GlaxoSmithKline (consultant), Janssen-Ortho-McNeil (consultant, speakers bureau), Eli Lilly and Company (consultant, speakers bureau, grant/research support), H. Lundbeck A/S (consultant, speakers bureau), Organon (consultant), Pfizer Inc (consultant), Shire (consultant), Solvay/Wyeth (consultant, speakers bureau).

The staff of Veritas Institute for Medical Education, Inc. has nothing to disclose.

Off-Label/Investigational Uses of Drugs
Participants are advised that this CME activity will contain references to the unlabeled/unapproved/investigational uses of drugs to treat patients with bipolar disorder.

Disclaimer
The opinions expressed in this activity are those of the faculty and do not necessarily reflect those of Veritas Institute for Medical Education, Inc. or Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals Inc. administered by Ortho-McNeil Janssen Scientific Affairs, LLC. Please consult the appropriate package insert for full prescribing information on all drug therapies discussed.

Editorial Board

Editor
Roger S. McIntyre, MD, FRCPC

Associate Professor, Psychiatry and Pharmacology
University of Toronto
Head, Mood Disorders Psychopharmacology Unit
University Health Network
Toronto, Ontario, Canada

Learning Objectives
1. You will be better able to individualize evidence- and guideline-based polypharmacologic regimens when appropriate during both the acute and maintenance phases in patients with bipolar disorder.
2. You will be better able to recognize, monitor, and treat medical comorbidities and adverse events in patients with bipolar disorder.

Copyright © 2009 Veritas Institute for Medical Education, Inc. All rights reserved.